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Mouse Models
Service Internal Rate External non-profit External for-profit Indel $7,008.00 $8,410.00 $9,672.00 Missense $12,465.00 $14,958.00 $17,202.00 Epitope tagging/small insertion (<150nt) $12,748.00 $15,298.00 $17,593.00 Large deletion $15,272.00 $18,326.00 $21,075.00 Conditional allele (flox/Frt) $26,542.00 $31,850.00 $36,628.00 Large KI (<800 nucleotides) $20,732.00 $24,878.00 $28,610.00 Large KI (>800 nucleotides) $27,298.00 $32,758.00 $37,672.00 ROSA locus KI $21,439.00 $25,727.00 $29,586.00
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Rat Models
Service Internal Rate External non-profit External for-profit Indel $10,512.00 $12,614.00 $14,506.00 Missense $18,697.00 $22,436.00 $25,801.00 Epitope tagging/small insertion (<150nt) $19,122.00 $22,946.00 $26,388.00 Large deletion $22,908.00 $27,490.00 $31,614.00 Conditional allele (flox/Frt) $39,813.00 $47,776.00 $54,942.00 Large KI (>200b) $31,098.00 $37,318.00 $42,916.00 Large KI (>1000kb) $40,947.00 $49,136.00 $56,506.00 ROSA locus KI $32,158.00 $38,590.00 $44,379.00
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Transformed Cell Lines
Service Internal Rate External non-profit External for-profit Indel $7,588.00 $9,106.00 $10,472.00 Missense $7,746.00 $9,295.00 $10,689.00 Epitope tagging/small insertion (<150nt) $7,970.00 $9,564.00 $10,999.00 Large deletion $8,355.00 $10,026.00 $11,530.00 Conditional allele (flox/Frt) $16,853.00 $20,224.00 $23,258.00 Large KI (>200b) $17,521.00 $21,025.00 $24,179.00 Large KI (>1000kb) $18,571.00 $22,285.00 $25,628.00 ROSA locus KI $17,997.00 $21,596.00 $24,835.00 Transduction Condition Optimization $2,800.00 $3,360.00 $3,864.00
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iPSC Models
Service Internal Rate External non-profit External for-profit Indel $8,141.00 $9,769.00 $11,234.00 Missense $8,293.00 $9,952.00 $11,445.00 Epitope tagging/small insertion (<150nt) $8,504.00 $10,205.00 $11,736.00 Large deletion $8,867.00 $10,640.00 $12,236.00 Conditional allele (flox/Frt) $16,880.00 $20,256.00 $23,294.00 Large KI (>200b) $17,510.00 $21,012.00 $24,164.00 Large KI (>1000kb) $18,500.00 $22,200.00 $25,530.00 ROSA locus KI $17,959.00 $21,551.00 $24,784.00
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A La Carte Services
Service Internal Rate External non-profit External for-profit Pronuclear injection into C57BL6/J embryos and transfer (120-200 zygotes) $6,000.00 $7,200.00 $8,280.00 Sperm cryopreservation (with verification) $2,000.00 $2,400.00 $2,760.00 Sperm cryopreservation (without verification) $800.00 $960.00 $1,104.00 Cryopreservation of IVF embryos $1,000.00 $1,200.00 $1,380.00 In vitro fertilization and embryo transfer $2,000.00 $2,400.00 $2,760.00 Embryo thaw and transfer $900.00 $1,080.00 $1,242.00 Cryo Storage (per year/per line) $100.00 $120.00 $138.00 IVF $2,000.00 $2,400.00 $2,760.00 Microinjection (CRISPR, Transgene) $6,000.00 $7,200.00 $8,280.00 sgNRA synthesis $250.00 $300.00 $345.00 Gene KO pool (cell lines) $3,000.00 $3,600.00 $4,140.00
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Other Services/Fees
Service Internal Rate External non-profit External for-profit Statement-of-work (Design of allele, PCR genotyping strategies, HDR templates design, etc.) $2,000.00 $2,400.00 $2,760.00 Plasmids $50.00 $60.00 $69.00 Consultation fees (per hour) $250.00 $300.00 $345.00 Design (per hour) $1,500.00 $1,800.00 $2,070.00
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