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The Center for Medical Genomics at Indiana University School of Medicine offers state-of-the-art genomic technology and staff expertise to investigators conducting biomedical research. The center is equipped with a variety of advanced genomics instrumentation and offers services at all stages of the experiment.

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Please contact the Center for Medical Genomics program manager for a service quote or to schedule a consultation.

The Center for Medical Genomics offers DNA/RNA quantification, DNA quality control and fragment-size analysis, RNA quality (measure of fragmentation/degradation), and miRNA quality. DNA/RNA Analysis services include quality/quantity assessment as well as shearing and sample extraction. Instruments include NanoDrop, Agilent 2100 Bioanalyzer, Qubit Fluorometer, and Covaris S2 Focused-ultrasonicator.

Single cell analysis includes Single Cell RNA-seq, Single Nucleus RNA-seq, Single Cell ATAC-seq, Single Cell Multiome ATAC + Gene Expression. and Single Cell Immune Profiling. The center is equipped with three 10x Genomics Chromium Systems. Investigators are responsible for preparing high-quality single-cell suspension from biological specimens. FAQs about single cell studies give additional details about this service.

Spatial transcriptomics is a relatively new, groundbreaking molecular profiling method that allows researchers to measure all the gene activity in a tissue sample and map where the activity is occurring. The Center for Medical Genomics offers Visium Spatial Gene Expression for FFPE and fresh frozen tissues. 

The Center for Medical Genomics offers whole genome sequencing, whole exome sequencing, gene panel target sequencing, DNA methylation, TELL-seq, ChIP-seq and amplicon sequencing.

RNA sequencing services include whole transcriptome sequencing, mRNA sequencing, miRNA sequencing, and targeted RNA sequencing. FAQs about RNA-sequencing give additional details about this service.

Metagenomics services include 16S sequencing and shotgun sequencing.